Full Name: Li Hong-Yu

Position：Institute Director, Professor, PhD Supervisor

E-mail: lihy@lzu.edu.cn

Address:

Room 4027, Qinbo Building Institute of Microbiology and Biochemical Pharmacy, School of Pharmacy, Lanzhou University, Lanzhou 730000, China

Education

Received BSc in Plant Physiology from the Department of Biology at Lanzhou University in 1986. In the same year, assigned to Gansu Agricultural University be engaged in teaching and research on plant physiology.ReceivedMSc in Plant Physiology from Lanzhou University in 1993. Graduated from plant protection institute of Nanjing Agricultural University with PhD in 1996, majoring in Plant Pathology. Then studied in Biology Post-Doctoral Research Station at Lanzhou University of the same year.

Professional Background

Sep.1999~present

worked at the College of Life Sciences and School of Pharmacy of Lanzhou University.

Teaching

Courses:

Progress of Modern Biotechnology (for graduate students) 

Research Interests

Research experience

[1] Gansu intellectual property project (17ZC1LA015); Patent protection practice research of Chinese traditional medicine internationalization, director.

[2] the Horizontal project of Shenzhen Aimin Medicine Technology Co., Ltd., the Effect ofLienal Polypeptide Injection in the treatment of thrombocytopenia, director.

[3] the Horizontal project of Shanghai Zhonghua Pharmaceutical Co., Ltd., the new indications of Dragon Tiger Panacea, director.

Research Interests

1. Biopharmaceuticals;

2. High throughput Drug Screening Technology;

3. Pharmaceutical Biotechnology

Honor and Awards

Representative Publications

[1] Ru Y, Zhi DJ, Guo DD, Wang Y, Li Y, Wang MZ, Wei SZ, Wang HQ, Wang N, Che JM, Li HY. (2016) Expression and bioactivity of recombinant human serum albumin and dTMP fusion proteins in CHO cells. ApplMicrobiolBiotechnol. 100(17):7565-75.
　　[2] Zhang WM, Zhi DJ, Ren H, Wang D, Wang X, Zhang ZX, Fei DQ, Zhu HM, Li HY (2016) Shengmai Formula Ameliorates Pathological Characteristics in AD C. elegans. Cell MolNeurobiol. 36(8):1291-1302
　　[3] Wang MZ, Zhi DJ, Xian J, Ru Y, Wei SZ, Wang N, Liu YY, Wang HQ, Pei YJ, Song MJ, Li Y, Li HY (2016) Functional expression of human serum albumin-tandem thrombopoietin mimetic peptide fusion protein as a novel thrombopoietin analog in Pichiapastoris. BiotechnolLett. 38(5):779-85.
　　[4] Chen P, Yan L, Wu ZR, Li SY, Bai ZT, Yan XJ, Wang NB, Liang N, Li HY (2016) A microbial transformation using Bacillus subtilis B7-S to produce natural vanillin from ferulic acid. Sci Rep. 6:20400.
　　[5] Wang MZ, Zhi DJ, Wang HQ, Ru Y, Ren H, Wang N, Liu YY, Li Y, Li HY (2016) TAT-HSA-α-MSH fusion protein with extended half-life inhibits tumor necrosis factor-α in brain inflammation of mice. ApplMicrobiolBiotechnol. 100(12):5353-61
　　[6] Liu, Y., Zhi, DJ., Li, MH., Liu, DL., Wang, X., Wu, ZR., Zhang, ZX., Fei, DQ., Li, Y., Zhu, HM., Xie, QJ., Yang, H., & Li, HY.，(2016) Shengmai Formula suppressed over-activated Ras/MAPK pathway in C. elegans by opening mitochondrial permeability transition pore via regulating cyclophilin D. Scientific Reports. Sci Rep. 6:38943.