Full Name: Quanyi Zhao

Position: Ph.D，Professor

E-mail: zhaoqy@lzu.edu.cn

Address:

Institute of medicinal chemistry，School of Pharmacy，Lanzhou University, Gansu 730000, China

Education:

Sep.2000~Jun.2005

Ph.D. degree at the Lanzhou Institute of Chemical Physics (LICP) of the Chinese Academy of Sciences (CAS), Major in catalysis

Sep.1991~Jun.1995

B.Sc. degree at School of Pharmacy, Lanzhou Medical College, Major in Pharmacy

Professional Background:

Apr.2015~present

Professor of medicinal chemistry, School of Pharmacy

Jun. 2009~Jun. 2010

Visiting Scholar at Toronto University

Apr. 2007~Apr.2015

Associate Professor of medicinal chemistry, School of Pharmacy

Jun.19955~Apr. 2007

Lecturer of medicinal chemistry, School of Pharmacy

Teaching:

Courses:

Modern medicinal chemistry (for graduate students)

Organic chemistry (for undergraduate students)

Textbook:

< Advanced medicinal chemisty>, Chemical industry Press, Nov. 2011.

< organic chemistry>, People’s Medical Publishing House, 2016

Research Interests:

Research experience

Responsible for and participate in research projects: “ Natural Science Foundation of Gansu Province in 2006; 2006 Interdisciplinary Fund of Lanzhou University; 2010 Central University Foundation; National Natural Science Foundation 2011; Natural Science Foundation of Gansu Province in 2011; 2012 Research Start-up Fund for returnees; Project of Lanzhou Science and Technology Development Plan 2014”.

Research Interests

1. Drug discovery, synthesis and modification of the lead compounds.

2. Metabolism and toxicity of drug.

3. Carbonyl metal CO releasing molecules and H2S donors.

Honor and Awards:

Representative Publications:

1.Quan-Yi Zhao, Wei-Qiang Zhang, Yu-Hua Zhang, Bin Hu, Yuan-Qi Yin, Chun-Gu Xia,   Synthesis of Optically Active Tetrahedral Clusters through Ester-exchange Catalyzed by Lipase, organometallics, 2004, 23(3), 817-822.

2.ZHAO, Quan-Yi;  ZHANG, Yu-Hua;  HU,Bin;  ZHANG, Wei-Qiang;  ZHU, Bao-Hua;  YIN,Yuan-Qi;  XIA,Chun-Gu.  Asymmetric Inducing Synthesis of Optically Active Tetrahedral Cluster Containing SMCoW Core   Chin. J. Chem  2004, 22 (7), 757-760.

3.Quan-Yi Zhao, Wei-Qiang Zhang, Yu-Hua Zhang, Bin Hu,  Yuan-Qi Yin , Chun-Gu Xia  Synthesis and Reaction of Chiral Tetrahedral clusters containing an COOCH3 Functional Group  Journal of Chemical Research  2003, (12), 802-803.

4.Quan-Yi Zhao, Bin Hu, Wei-Qiang Zhang, Chun-Gu Xia Synthesis and Resolution of Tetrahedral Cluster Containing SeRuCoMo Core  Journal of Chemical Research  2004, (1), 76-77.

5. Zhao, Quanyi ，Hu, Bin，Zhang, Yuhua，Li, Wenzhi，Xia, Chungu，Yin, Yuanqi，Resolution of chiral metal tetrahedral compounds through transamidation or transacetylation using lipase as a catalyst，Tetrahedron: Asymmetry，2009.6.19，20（11）：1235~1238.

6. Meng Li, Jili Li, Taofeng Zhang, Quanyi Zhao, Jie Cheng , Bin Liu, Zhen Wang, Libo Zhao, Chenwei Wang. European Journal of Medicinal Chemistry 138 (2017) 51-65.

7.Yaguo Gong，Taofeng Zhang，Meng Li，Na Li，Yawen Zheng，Quanyi Zhao*，Yonglin Chen，Bin Liu，Toxicity, bio-distribution and metabolism of CO-releasing molecules based on cobalt，Free Radical Biology and Medicine，2016，97：362~374.

8. Taofeng Zhang，Yaguo Gong，Meng Li，Na Xi，Yawen Zheng，Quanyi Zhao*，Yonglin Chen，Bin Liu，Syntheses, properties and bio-activities of water-soluble CO-releasing molecule based on manganese，Journal of biological inorganic chemistry，2016，21：807~824

9. Yali Chen，Qian Yan，Mei Zhong，Quanyi Zhao*，Junxi Liu，Duolun Di,，Jinxia Liu，Study on pharmacokinetics and tissue distribution of the isocorydine derivative (AICD) in rats by HPLC-DAD method. Acta Pharmaceutica Sinica B，2015, 5（3）：238~245.

10. Huapeng Liu，Yaguo Gong，Taofeng Zhang，Na Li，Yonglin Chen, Quanyi Zhao*，Bin Liu，Yawen Zheng，Syntheses, Cytotoxicity and Properties of CO Releasing Molecules Containing Acetyl Salicylamide-3-pyridine，Chin. J. Chem，2015，33：739~748.

11. Yaguo Gong，Taofeng Zhang，Huapeng Liu，Yawen Zheng，Na Li，Quanyi Zhao*, Yonglin Chen，Bin Liu，Synthesis, toxicities and cell proliferation inhibition of CO-releasing molecules containing cobalt. Transition Met Chem，2015，40（4）：413~426.

12. Wang, Pengpeng; Liu, Huapeng; Zhao, Quanyi*; Chen, Yonglin; Liu, Bin; Zhang, Baoping; Zheng, Qian. Syntheses and evaluation of drug-like properties of CO-releasing molecules containing ruthenium and group 6 metal. European Journal of Medicinal Chemistry，2014，74：199-215.

13. Liu, Huapeng; Wang, Pengpeng; Zhao, Quanyi*; Chen, Yonglin; Liu, Bin; Zhang, Baoping; Zheng, Qian. Syntheses, toxicity and bio-distribution of CO releasing molecules containing M( CO) 5 ( M = Mo, W and Cr)，Applied organometallic Chemistry，2014, 28（3）：169~179

14. Zhao, Hanqing; Sun, Wei; Miao, Chengxia; Zhao, Quanyi,* Aerobic oxidation of secondary alcohols using NHPI and iron salt as catalysts at room temperature. Journal of Molecular Catalysis A: Chemical，2014，393（7）：62~67.